21-Oct-2026 18:33:51
ZYDUSLIFE : ZYLIDAC BIO PARTNERS WITH PROLIFIC MACHINES FOR GMP SCALE-UP
• Zylidac Bio, a fully integrated biologics CDMO within the Zydus group, to scale Prolific's light-controlled cell line development platform into GMP production • Zylidac to first complete tech transfer of Prolific's process at 50-litre scale, then scale client programs to 250 litres and into GMP manufacturing • Prolific's illumination hardware works with Zylidac's existing bioreactors, eliminating need for customers to build new manufacturing infrastructure • Prolific reported 21 g/L in a 15-day intensified fed-batch CHO run for a mAb at small scale, plus up to three-fold titer increases for other complex formats • Creates end-to-end pathway from cell line development at Prolific to scale-up, drug substance, drug product, fill-finish and packaging at Zylidac's 83,000 sq ft Emeryville site
Zydus Lifesciences Limited
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